Breast Cancer Association Consortium (BCAC)

UCAM (participant 2) is responsible for BCAC. BCAC is a consortium of 45 breast cancer case-control studies that include >50,000 cases of breast cancer and >50,000 matched controls from all over the world. A detailed description is found at ( BCAC has undertaken four rounds of genotyping.

These have led to the confirmation of five novel breast cancer loci identified through a genome wide scan and the identification of CASP8 D302H as a susceptibility allele, with papers in Nature, Nature Genetics and JNCI.

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